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Equipped with current GMP certification, Hejia Pharma produces a range of cephalosporin antibiotic APIs and formulations, supported by advanced processes and facilities for traditional Chinese medicine (TCM) extraction and preparation. Its products dominate domestic and international markets, solidifying its reputation as a global leader in cephalosporin antibiotics, while expanding into high-quality TCM offerings.

  • APG
    APG

    1.Personal Care Applications
    Alkyl Polyglucosides (APG) are highly valued in the personal care industry for their exceptional mildness and safety. As a nonionic surfactant derived from natural glucose and plant-based fatty alcohols, APG aligns perfectly with modern consumers' demand for "green chemistry." In infant care products, APG serves as an ideal alternative to traditional SLS/SLES due to its tear-free formulation, effectively cleansing without compromising the delicate skin barrier of infants. For sensitive skin care, APG’s pH closely matches the skin’s natural acidity, minimizing irritation or allergic reactions, making it particularly suitable for facial cleansers, makeup removers, and other products. In premium shampoos, APG generates rich, fine lather while improving hair manageability and reducing frizz. Additionally, APG is widely used in oral care as a toothpaste foaming agent, gently cleansing the mouth without affecting taste perception. Its superior biocompatibility makes it the surfactant of choice for organic-certified cosmetics.

     

    2.Household Cleaning Applications
    In the household cleaning sector, APG is driving the green cleaning revolution. Compared to traditional petroleum-based surfactants, APG exhibits higher surface activity and superior environmental compatibility. For dishwashing, APG rapidly breaks down grease and rinses easily without residue, making it ideal for premium dish detergent formulations. In laundry products, APG synergizes well with enzymes, enhancing low-temperature washing efficiency and meeting the demands of concentrated liquid detergents. For hard surface cleaners, APG effectively penetrates stains while remaining gentle on materials like furniture and flooring. Its low-foaming properties make it suitable for automatic dishwasher detergents, preventing foam overflow. Critically, APG biodegrades rapidly in wastewater systems, avoiding environmental persistence and complying with EU Ecolabel standards.

     

    3.Agricultural Applications
    In modern agriculture, APG plays an increasingly vital role. As a pesticide adjuvant, APG improves the wetting and spreading of formulations, enhancing active ingredient adhesion—especially on waxy-leaf crops. In foliar fertilizers, APG promotes nutrient absorption and utilization efficiency. It also aids seed coating agents, ensuring uniform chemical distribution and boosting germination rates. For soil remediation, APG disperses contaminants and accelerates microbial degradation. Compared to traditional agrochemical adjuvants, APG demonstrates lower ecotoxicity, posing minimal risk to beneficial insects and aquatic life, making it ideal for organic farming and green food production. Additionally, APG is used in post-harvest produce washing to remove pesticide residues without compromising quality.

     

    4.Industrial Applications
    APG shows broad potential across industrial sectors. In textiles, it enhances fiber wettability during pre-treatment and improves dye penetration in printing processes. For papermaking, APG acts as an effective deinking agent, boosting recycled paper quality. In oil extraction, APG’s temperature and salt resistance make it a valuable enhanced oil recovery agent. In metalworking, APG serves as an eco-friendly degreaser that removes oil without corrosion. In construction, APG improves concrete workability as an additive. Its biodegradability also simplifies wastewater treatment in industrial equipment cleaning applications.

  • Active Pharmaceutical Ingredients (APIs)
    Active Pharmaceutical Ingredients (APIs)

    Cephalosporin APIs, a critical subclass of β-lactam antibiotics, exhibit broad-spectrum antibacterial activity and are widely used in clinical infection treatment.

     

    Cefazolin Sodium: A first-generation cephalosporin with strong Gram-positive activity, suitable for respiratory and skin infections. Its stability makes it ideal for injectable formulations.

     

    Cefotaxime Sodium: A third-generation cephalosporin effective against Gram-negative bacteria (e.g., Escherichia coli, Klebsiella pneumoniae), used for severe and nosocomial infections.

     

    Ceftezole Sodium: Combines first- and third-generation characteristics, effective against resistant strains, and widely used for perioperative infection prophylaxis.

     

    Cefoperazone Sodium: Exhibits anti-Pseudomonas aeruginosa activity, often combined with β-lactamase inhibitors for complex abdominal infections and sepsis.

  • Intermediates
    Intermediates

    Cephalosporin intermediates are crucial for API synthesis, directly impacting drug efficacy and safety.

     

    AE Active Ester: A key starting material for multiple cephalosporins, offering excellent chemical stability and high reaction yields.

     

    Triazine Ring and Aminothiazole Acid: Core structures for cephalosporin frameworks, where purity determines subsequent reaction efficiency.

     

    Cefazolin Acid and Cefotaxime Acid: Side-chain intermediates undergo strict process control to ensure API crystallinity and purity.

     

    Ceftriaxone Sodium Crude: Refined into pharmacopeia-compliant APIs via mature purification processes.

     

     

  • Precision Polyurethane Solutions For Superior Performance
    Precision Polyurethane Solutions For Superior Performance

    Cephalosporin intermediates are crucial for API synthesis, directly impacting drug efficacy and safety.

     

    AE Active Ester: A key starting material for multiple cephalosporins, offering excellent chemical stability and high reaction yields.

     

    Triazine Ring and Aminothiazole Acid: Core structures for cephalosporin frameworks, where purity determines subsequent reaction efficiency.

     

    Cefazolin Acid and Cefotaxime Acid: Side-chain intermediates undergo strict process control to ensure API crystallinity and purity.

     

    Ceftriaxone Sodium Crude: Refined into pharmacopeia-compliant APIs via mature purification processes.

     

     

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