Cefazolin Sodium (CAS No.: 27164-46-1)

Cefazolin Sodium (CAS No.: 27164-46-1)


Cefazolin Sodium is a first-generation cephalosporin antibiotic material primarily used for its broad-spectrum bactericidal activity against Gram-positive organisms. It is widely applied in the production of injectable antibiotics and is valued for its rapid onset and reliable pharmacokinetic properties. Cefazolin Sodium works by inhibiting bacterial cell wall synthesis and is especially effective in treating infections of the respiratory tract, skin, soft tissue, bones, joints, and urinary tract. Its sodium salt form enhances water solubility, making it ideal for sterile injectable formulations. Produced under strict GMP standards, Cefazolin Sodium ensures pharmaceutical-grade purity, stability, and safety, making it a key active pharmaceutical ingredient (API) for both clinical and surgical use.

Introduction

Cefazolin Sodium is the sodium salt form of Cefazolin, a β-lactam antibiotic belonging to the cephalosporin class. It has excellent antibacterial activity, particularly against staphylococci and streptococci, making it an important choice for preoperative prophylaxis and treatment of moderate infections. The compound is known for its fast-acting therapeutic effect and favorable safety profile.

 

Application

Cefazolin Sodium is extensively used in hospital settings for the prevention and treatment of bacterial infections. It is the active ingredient in sterile injectable formulations for perioperative prophylaxis and treatment of infections involving the skin, bone, urinary tract, and respiratory system. Its dependable spectrum of activity and stability in solution make it a mainstay in emergency and surgical medicine.

 

Packaging

The product is typically packed in pharmaceutical-grade containers such as double polyethylene bags inside fiber drums, or sterile glass vials for injectable manufacturing purposes. Standard packaging sizes range from 10 kg to 25 kg per drum, with customized packaging available upon request to meet individual manufacturing needs.


Usage Instructions

Cefazolin Sodium is intended for use in injectable antibiotic preparations and must be handled under sterile manufacturing conditions. It is typically reconstituted with sterile water for injection or other suitable solvents as per pharmacopeial guidelines. Dosage and administration depend on the infection type, severity, and patient condition, and should be determined by a licensed medical professional. Store in a cool, dry, and well-ventilated place, away from moisture and light to preserve potency and stability.

 

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